Magnetic manipulation of gravitational force during cell culture için kapak resmi
Magnetic manipulation of gravitational force during cell culture
Başlık:
Magnetic manipulation of gravitational force during cell culture
Yazar:
Kaptan, Sinem, author.
Yazar Ek Girişi:
Fiziksel Tanımlama:
xi, 60 leaves: charts;+ 1 computer laser optical disc.
Özet:
With the development of space technologies, one of the most important problems that astronauts will encounter in the planned manned space travels to the Moon and Mars in the near future is the reduced (<1g) gravitational force. Knowledge of the biological effects of partial gravitational force on long-duration space missions is limited. Therefore, it is important to investigate effects of partial gravitational force on physiological adaptation mechanisms. However, methodology to induce partial gravity is expensive and subjected to ethical constraints, therefore there is a need for new ground-based simulation platforms that are able to mimic the partial gravitational force. In this master's thesis, a new partial gravity platform was developed that manipulates gravitational force during cell culture using magnetic fields. First, the platform system was designed and fabricated, and then detailed protocols were described for its use in cell culture. In addition, the effect of simulated partial gravity on cell viability and morphology at the cellular level was examined. The results show that the simulated partial gravity of Mars and the Moon affects the viability and morphology of cells. This new low-cost and easy-to-use partial gravity platform can be used as a ground-based simulation system for gravitational space biology research at the cellular and molecular levels.
Yazar Ek Girişi:
Tek Biçim Eser Adı:
Thesis (Master)--İzmir Institute of Technology:Bioengineering.

İzmir Institute of Technology:Bioengineering --Thesis (Master).
Elektronik Erişim:
Access to Electronic Versiyon.
Ayırtma: Copies: