Biophotonics - Optical Science and Engineering for the 21st Century - Roeland Van Wijk, PhD. and Prof. Dr. Xun Shen Biophotonics, the science of generating and harnessing light photons to image, detect and manipulate biological materials, offers great hope for the early detection of diseases and for new modalities of light-guided and light-activated therapies. It offers a powerful tool for studying molecular events, such as gene expression, protein-protein interaction, spatial and temporal distribution of the molecules of biological interest, and many chemico-physical processes in living cells and living organisms. Biophotonics - Optical Science and Engineering for the 21st Century introduces the basic experimental and theoretical framework, the technical problems, and the wide field of applications in biotechnology, biomedical engineering, engineering, medicine, pharmacology, environmental science, life sciences, and clinical sciences. Biophotonics: Optical Science and Engineering in the 21st Century serves as an ideal aid to the research and development of these areas integrating light, photonics, and biological systems. Key topics include: Fluctuation Correlation Spectroscopy in Cells: Determination of Molecular Aggregation Using GFP and FRET Technologies for Studying Signaling Mechanisms of Apoptosis in a Single Living Cell Study on Protein-Protein Interaction in Single Living Cells Functional Optical Coherence Tomography: Simultaneous In Vivo Imaging of Tissue Structure and Physiology Imaging –Photo- and Sonodynamic Diagnosis of Cancer Mediated by Chemiluminescence Probes Biophotonic Analysis of Spontaneous Self-Organizing Oxidative Processes in Aqueous Systems Biophoton Emission and Defense Systems in Plants Biophotonics - Optical Science and Engineering for the 21st Century stands as a valuable resource for advanced undergraduate, graduate students and researchers in biomedical engineering, biotechnology, engineering, chemistry, physics, life sciences, and clinical sciences. Editors: Xun Shen Professor, Institute of Biophysics, Chinese Academy of Sciences Beijing, China Roeland Van Wijk Professor, Department of Molecular Cell Biology, Utrecht University, Utrecht, The Netherlands.