In South Boston, the Massachusetts State Police are waging a war on Irish-American organized crime. Undercover cop Billy Costigan is assigned to infiltrate the mob syndicate, which is run by gangland chief Frank Costello. Billy quickly gains Costello's confidence. Colin Sullivan is a hardened young criminal who has infiltrated the police department as an informer for the syndicate. Colin is rising to a position of power within the Special Investigation Unit. Each man becomes deeply consumed by his double life, gathering information about the plans and counter-plans of the operations he has penetrated. But when it becomes clear to both the mob and the police that there are moles in their midst, Billy and Colin are suddenly thrust into danger. Afraid of being caught and exposed to the enemy, each must race to uncover the identity of the other man in time to save himself.